Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors
Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors that control the expression of genes involved in a variety of physiologic processes, through heterodimerization with retinoid X receptor and complex formation with various cofactors. Drugs or treatment regi...
Main Authors: | , , , , , , , , |
---|---|
Format: | Online |
Language: | English |
Published: |
WILEY-VCH Verlag
2012
|
Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504387/ |