Comparative Molecular Profiling of the PPARα/γ Activator Aleglitazar: PPAR Selectivity, Activity and Interaction with Cofactors

Peroxisome proliferator-activated receptors (PPARs) are a family of nuclear hormone receptors that control the expression of genes involved in a variety of physiologic processes, through heterodimerization with retinoid X receptor and complex formation with various cofactors. Drugs or treatment regi...

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Bibliographic Details
Main Authors: Dietz, Michel, Mohr, Peter, Kuhn, Bernd, Maerki, Hans Peter, Hartman, Peter, Ruf, Armin, Benz, Jörg, Grether, Uwe, Wright, Matthew B
Format: Online
Language:English
Published: WILEY-VCH Verlag 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504387/