Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations

Rett syndrome induced pluripotent stem cell-derived neurons reveal novel neurophysiological alterations

Rett syndrome (RTT) is a neurodevelopmental autism spectrum disorder caused by mutations in the methyl-CpG-binding protein 2 (MECP2) gene. Here, we describe the first characterization and neuronal differentiation of induced pluripotent stem (iPS) cells derived from Mecp2-deficient mice. Fully reprog...

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Bibliographic Details
Main Authors: Farra, N, Zhang, W-B, Pasceri, P, Eubanks, J H, Salter, M W, Ellis, J
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504383/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3504383/

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