Generation of anti-Notch antibodies and their application in blocking Notch signalling in neural stem cells
► Potent antibodies that antagonise mouse and human Notch signalling are generated. ► Receptor specific inhibition of Notch1 and 2 signalling is demonstrated. ► Antibody mediated inhibition of Notch influences neural stem cell differentiation.
Bibliographic Details
| Main Authors: |
Falk, Ronny,
Falk, Anna,
Dyson, Michael R.,
Melidoni, Anna N.,
Parthiban, Kothai,
Young, Joyce L.,
Roake, Wendy,
McCafferty, John |
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| Format: | Online
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| Language: | English |
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| Published: |
Academic Press
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502869/
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