Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome
Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericardit...
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2012
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pubmed-35028052012-11-29 Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome Makimoto, Go Asano, Michiko Fujimoto, Nobukazu Fuchimoto, Yasuko Ono, Katsuichiro Ozaki, Shinji Taguchi, Koji Kishimoto, Takumi Case Report Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericarditis. We report a case of SS presenting initially with bilateral pleural effusions. A 63-year old man was admitted to our hospital with a one-month history of cough, dyspnea, and right chest pain. Chest-computed tomography revealed bilateral pleural effusions. Serum anti-SS-A antibody titer was 1 : 256. Ophthalmological examination revealed a positive Schirmer test. Lip biopsy showed atrophy and plasmacytic infiltration of the salivary gland. Corticosteroid treatment was initiated. Pleural effusions were almost completely resolved by day 30. The patient has not experienced any recurrence. Hindawi Publishing Corporation 2012 2012-11-01 /pmc/articles/PMC3502805/ /pubmed/23198246 http://dx.doi.org/10.1155/2012/640353 Text en Copyright © 2012 Go Makimoto et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Makimoto, Go Asano, Michiko Fujimoto, Nobukazu Fuchimoto, Yasuko Ono, Katsuichiro Ozaki, Shinji Taguchi, Koji Kishimoto, Takumi |
spellingShingle |
Makimoto, Go Asano, Michiko Fujimoto, Nobukazu Fuchimoto, Yasuko Ono, Katsuichiro Ozaki, Shinji Taguchi, Koji Kishimoto, Takumi Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome |
author_facet |
Makimoto, Go Asano, Michiko Fujimoto, Nobukazu Fuchimoto, Yasuko Ono, Katsuichiro Ozaki, Shinji Taguchi, Koji Kishimoto, Takumi |
author_sort |
Makimoto, Go |
title |
Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome |
title_short |
Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome |
title_full |
Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome |
title_fullStr |
Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome |
title_full_unstemmed |
Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome |
title_sort |
bilateral pleural effusions as an initial presentation in primary sjögren's syndrome |
description |
Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericarditis. We report a case of SS presenting initially with bilateral pleural effusions. A 63-year old man was admitted to our hospital with a one-month history of cough, dyspnea, and right chest pain. Chest-computed tomography revealed bilateral pleural effusions. Serum anti-SS-A antibody titer was 1 : 256. Ophthalmological examination revealed a positive Schirmer test. Lip biopsy showed atrophy and plasmacytic infiltration of the salivary gland. Corticosteroid treatment was initiated. Pleural effusions were almost completely resolved by day 30. The patient has not experienced any recurrence. |
publisher |
Hindawi Publishing Corporation |
publishDate |
2012 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502805/ |
_version_ |
1611934112277331968 |