Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome

Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericardit...

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Main Authors: Makimoto, Go, Asano, Michiko, Fujimoto, Nobukazu, Fuchimoto, Yasuko, Ono, Katsuichiro, Ozaki, Shinji, Taguchi, Koji, Kishimoto, Takumi
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502805/
id pubmed-3502805
recordtype oai_dc
spelling pubmed-35028052012-11-29 Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome Makimoto, Go Asano, Michiko Fujimoto, Nobukazu Fuchimoto, Yasuko Ono, Katsuichiro Ozaki, Shinji Taguchi, Koji Kishimoto, Takumi Case Report Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericarditis. We report a case of SS presenting initially with bilateral pleural effusions. A 63-year old man was admitted to our hospital with a one-month history of cough, dyspnea, and right chest pain. Chest-computed tomography revealed bilateral pleural effusions. Serum anti-SS-A antibody titer was 1 : 256. Ophthalmological examination revealed a positive Schirmer test. Lip biopsy showed atrophy and plasmacytic infiltration of the salivary gland. Corticosteroid treatment was initiated. Pleural effusions were almost completely resolved by day 30. The patient has not experienced any recurrence. Hindawi Publishing Corporation 2012 2012-11-01 /pmc/articles/PMC3502805/ /pubmed/23198246 http://dx.doi.org/10.1155/2012/640353 Text en Copyright © 2012 Go Makimoto et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Makimoto, Go
Asano, Michiko
Fujimoto, Nobukazu
Fuchimoto, Yasuko
Ono, Katsuichiro
Ozaki, Shinji
Taguchi, Koji
Kishimoto, Takumi
spellingShingle Makimoto, Go
Asano, Michiko
Fujimoto, Nobukazu
Fuchimoto, Yasuko
Ono, Katsuichiro
Ozaki, Shinji
Taguchi, Koji
Kishimoto, Takumi
Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome
author_facet Makimoto, Go
Asano, Michiko
Fujimoto, Nobukazu
Fuchimoto, Yasuko
Ono, Katsuichiro
Ozaki, Shinji
Taguchi, Koji
Kishimoto, Takumi
author_sort Makimoto, Go
title Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome
title_short Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome
title_full Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome
title_fullStr Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome
title_full_unstemmed Bilateral Pleural Effusions as an Initial Presentation in Primary Sjögren's Syndrome
title_sort bilateral pleural effusions as an initial presentation in primary sjögren's syndrome
description Sjögren's syndrome (SS) is a systemic autoimmune disease characterized by sicca symptoms. Interstitial pulmonary fibrosis and tracheobronchial sicca are the most common symptoms of pulmonary involvement in primary SjS, and they are rarely accompanied by serositis such as pleuritis or pericarditis. We report a case of SS presenting initially with bilateral pleural effusions. A 63-year old man was admitted to our hospital with a one-month history of cough, dyspnea, and right chest pain. Chest-computed tomography revealed bilateral pleural effusions. Serum anti-SS-A antibody titer was 1 : 256. Ophthalmological examination revealed a positive Schirmer test. Lip biopsy showed atrophy and plasmacytic infiltration of the salivary gland. Corticosteroid treatment was initiated. Pleural effusions were almost completely resolved by day 30. The patient has not experienced any recurrence.
publisher Hindawi Publishing Corporation
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502805/
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