CD161+CD4+ T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ

Hepatitis C virus infection is a major cause of chronic liver disease. CD4+ T cells play a key role in disease outcome. However, the critical functions and associated phenotypes of intrahepatic CD4+ T cells are not well defined. We have previously shown that CD8+ T cells expressing the C type lectin...

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Bibliographic Details
Main Authors: Kang, Yu-Hoi, Seigel, Bianca, Bengsch, Bertram, Fleming, Vicki M., Billerbeck, Eva, Simmons, Ruth, Walker, Lucy, Willberg, Chris B., Barnes, Eleanor J., Bhagwanani, Anisha, Oo, Ye H., Blum, Hubert E., Adams, David H., Thimme, Robert, Klenerman, Paul
Format: Online
Language:English
Published: Frontiers Media S.A. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3502006/