Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology

Chronic cough is a common symptom carrying significant morbidity which can occur as a result of oesophageal dysmotility. Here we report 2 patients with musculoskeletal disease presenting with chronic cough to our tertiary cough clinic. Prior to referral both patients had been extensively investigate...

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Main Authors:	Pathmanathan, Sega, Morjaria, Jaymin B, Jackson, Warren, Morice, Alyn H
Format:	Online
Language:	English
Published:	BioMed Central 2012
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500721/

id	pubmed-3500721
recordtype	oai_dc
spelling	pubmed-35007212012-11-20 Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology Pathmanathan, Sega Morjaria, Jaymin B Jackson, Warren Morice, Alyn H Case Report Chronic cough is a common symptom carrying significant morbidity which can occur as a result of oesophageal dysmotility. Here we report 2 patients with musculoskeletal disease presenting with chronic cough to our tertiary cough clinic. Prior to referral both patients had been extensively investigated to determine the basis of their cough, with no cause found. Oesophageal studies, using high resolution oesophageal manometry, demonstrated oesophageal dysmotility with consequent airway reflux. Anti-reflux therapy resulted in a good response in both patients. These are the first reports of the recently developed technique of high resolution manometry aiding the diagnosis of chronic cough. This technique may provide important clues into aetiological mechanism in patients with conditions predisposing to reflux into the airways. BioMed Central 2012-09-28 /pmc/articles/PMC3500721/ /pubmed/23021351 http://dx.doi.org/10.1186/1745-9974-8-6 Text en Copyright ©2012 Pathmanathan et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type	Open Access Journal
institution_category	Foreign Institution
institution	US National Center for Biotechnology Information
building	NCBI PubMed
collection	Online Access
language	English
format	Online
author	Pathmanathan, Sega Morjaria, Jaymin B Jackson, Warren Morice, Alyn H
spellingShingle	Pathmanathan, Sega Morjaria, Jaymin B Jackson, Warren Morice, Alyn H Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology
author_facet	Pathmanathan, Sega Morjaria, Jaymin B Jackson, Warren Morice, Alyn H
author_sort	Pathmanathan, Sega
title	Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology
title_short	Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology
title_full	Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology
title_fullStr	Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology
title_full_unstemmed	Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology
title_sort	chronic cough in musculoskeletal disorders: using high resolution oesophageal manometry in search of an aetiology
description	Chronic cough is a common symptom carrying significant morbidity which can occur as a result of oesophageal dysmotility. Here we report 2 patients with musculoskeletal disease presenting with chronic cough to our tertiary cough clinic. Prior to referral both patients had been extensively investigated to determine the basis of their cough, with no cause found. Oesophageal studies, using high resolution oesophageal manometry, demonstrated oesophageal dysmotility with consequent airway reflux. Anti-reflux therapy resulted in a good response in both patients. These are the first reports of the recently developed technique of high resolution manometry aiding the diagnosis of chronic cough. This technique may provide important clues into aetiological mechanism in patients with conditions predisposing to reflux into the airways.
publisher	BioMed Central
publishDate	2012
url	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3500721/
_version_	1611924987924447232

Chronic Cough in Musculoskeletal disorders: Using high resolution oesophageal manometry in search of an Aetiology

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