Janus-faced role of SIRT1 in tumorigenesis
Silent mating type information regulation 1 (Sirtuin 1; SIRT1) has been reported to regulate various physiological events, such as aging and metabolism, via deacetylation of histone and nonhistone proteins. Notably, cumulative evidence supports the notion that SIRT1 has a Janus-faced role in tumorig...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
Blackwell Publishing Inc
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499659/ |