Defining the boundaries of species specificity for the Saccharomyces cerevisiae glycosylphosphatidylinositol transamidase using a quantitative in vivo assay
In eukaryotes, GPI (glycosylphosphatidylinositol) lipid anchoring of proteins is an abundant post-translational modification. The attachment of the GPI anchor is mediated by GPI-T (GPI transamidase), a multimeric, membrane-bound enzyme located in the ER (endoplasmic reticulum). Upon modification, GP...
| Main Authors: | , , |
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| Format: | Online |
| Language: | English |
| Published: |
Portland Press Ltd.
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3497722/ |