Nanoporous polymer ring resonators for biosensing
Optically resonant devices are promising as label-free biomolecular sensors due to their ability to concentrate electromagnetic energy into small mode volumes and their capacity for multiplexed detection. A fundamental limitation of current optical biosensor technology is that the biomolecular inter...
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| Format: | Online |
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Optical Society of America
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495877/ |
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pubmed-34958772012-12-20 Nanoporous polymer ring resonators for biosensing Mancuso, Matthew Goddard, Julie M. Erickson, David Research-Article Optically resonant devices are promising as label-free biomolecular sensors due to their ability to concentrate electromagnetic energy into small mode volumes and their capacity for multiplexed detection. A fundamental limitation of current optical biosensor technology is that the biomolecular interactions are limited to the surface of the resonant device, while the highest intensity of electromagnetic energy is trapped within the core. In this paper, we present nanoporous polymer optofluidic devices consisting of ring resonators coupled to bus waveguides. We report a 40% increase in polymer device sensitivity attributed to the addition of core energy- bioanalyte interactions. Optical Society of America 2011-12-20 /pmc/articles/PMC3495877/ /pubmed/22274347 http://dx.doi.org/10.1364/OE.20.000245 Text en ©2011 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Mancuso, Matthew Goddard, Julie M. Erickson, David |
| spellingShingle |
Mancuso, Matthew Goddard, Julie M. Erickson, David Nanoporous polymer ring resonators for biosensing |
| author_facet |
Mancuso, Matthew Goddard, Julie M. Erickson, David |
| author_sort |
Mancuso, Matthew |
| title |
Nanoporous polymer ring resonators for biosensing |
| title_short |
Nanoporous polymer ring resonators for biosensing |
| title_full |
Nanoporous polymer ring resonators for biosensing |
| title_fullStr |
Nanoporous polymer ring resonators for biosensing |
| title_full_unstemmed |
Nanoporous polymer ring resonators for biosensing |
| title_sort |
nanoporous polymer ring resonators for biosensing |
| description |
Optically resonant devices are promising as label-free biomolecular sensors due to their ability to concentrate electromagnetic energy into small mode volumes and their capacity for multiplexed detection. A fundamental limitation of current optical biosensor technology is that the biomolecular interactions are limited to the surface of the resonant device, while the highest intensity of electromagnetic energy is trapped within the core. In this paper, we present nanoporous polymer optofluidic devices consisting of ring resonators coupled to bus waveguides. We report a 40% increase in polymer device sensitivity attributed to the addition of core energy- bioanalyte interactions. |
| publisher |
Optical Society of America |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495877/ |
| _version_ |
1611923612544008192 |