CpG island hypermethylation-associated silencing of small nucleolar RNAs in human cancer

Much effort in cancer research has focused on the tiny part of our genome that codes for mRNA. However, it has recently been recognized that microRNAs also contribute decisively to tumorigenesis. Studies have also shown that epigenetic silencing by CpG island hypermethylation of microRNAs with tumor...

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Bibliographic Details
Main Authors: Ferreira, Humberto J., Heyn, Holger, Moutinho, Cátia, Esteller, Manel
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495749/