The Aldosterone-Mineralocorticoid Receptor Pathway Exerts Anti-Inflammatory Effects in Endotoxin-Induced Uveitis

We have previously shown that the eye is a mineralocorticoid-sensitive organ and we now question the role of mineralocorticoid receptor (MR) in ocular inflammation. The endotoxin-induced uveitis (EIU), a rat model of human intraocular inflammation, was induced by systemic administration of lipopolys...

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Bibliographic Details
Main Authors: Bousquet, Elodie, Zhao, Min, Ly, André, Leroux les Jardins, Guillaume, Goldenberg, Brigitte, Naud, Marie-Christine, Jonet, Laurent, Besson-Lescure, Bernadette, Jaisser, Frederic, Farman, Nicolette, De Kozak, Yvonne, Behar-Cohen, Francine
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494666/