Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15
Under physiological conditions, the trans-presentation of interleukin-15 (IL-15) by the IL-15 receptor α on the cell surface allows to confine and tune the IL-15-mediated immune responses. Therefore, targeting strategies that mimic this situation at the tumor sites appear especially promising for an...
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| Format: | Online |
| Language: | English |
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Landes Bioscience
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494650/ |
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pubmed-3494650 |
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oai_dc |
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pubmed-34946502012-11-20 Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 Müller, Dafne Author's View Under physiological conditions, the trans-presentation of interleukin-15 (IL-15) by the IL-15 receptor α on the cell surface allows to confine and tune the IL-15-mediated immune responses. Therefore, targeting strategies that mimic this situation at the tumor sites appear especially promising for anticancer immunotherapy. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494650/ /pubmed/23170284 http://dx.doi.org/10.4161/onci.20824 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Müller, Dafne |
| spellingShingle |
Müller, Dafne Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 |
| author_facet |
Müller, Dafne |
| author_sort |
Müller, Dafne |
| title |
Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 |
| title_short |
Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 |
| title_full |
Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 |
| title_fullStr |
Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 |
| title_full_unstemmed |
Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 |
| title_sort |
targeted cancer immunotherapy: mimicking physiological trans-presentation of il-15 |
| description |
Under physiological conditions, the trans-presentation of interleukin-15 (IL-15) by the IL-15 receptor α on the cell surface allows to confine and tune the IL-15-mediated immune responses. Therefore, targeting strategies that mimic this situation at the tumor sites appear especially promising for anticancer immunotherapy. |
| publisher |
Landes Bioscience |
| publishDate |
2012 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494650/ |
| _version_ |
1611923207104757760 |