Elongation Factor 1 alpha1 and Genes Associated with Usher Syndromes Are Downstream Targets of GBX2

Gbx2 encodes a DNA-binding transcription factor that plays pivotal roles during embryogenesis. Gain-and loss-of-function studies in several vertebrate species have demonstrated a requirement for Gbx2 in development of the anterior hindbrain, spinal cord, inner ear, heart, and neural crest cells. Ho...

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Bibliographic Details
Main Authors: Roeseler, David A., Sachdev, Shrikesh, Buckley, Desire M., Joshi, Trupti, Wu, Doris K., Xu, Dong, Hannink, Mark, Waters, Samuel T.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493575/