Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens

Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens

No vaccine has yet proven effective against the blood-stages of Plasmodium falciparum, which cause the symptoms and severe manifestations of malaria. We recently found that PfRH5, a P. falciparum-specific protein expressed in merozoites, is efficiently targeted by broadly-neutralizing, vaccine-induc...

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Bibliographic Details
Main Authors: Williams, Andrew R., Douglas, Alexander D., Miura, Kazutoyo, Illingworth, Joseph J., Choudhary, Prateek, Murungi, Linda M., Furze, Julie M., Diouf, Ababacar, Miotto, Olivo, Crosnier, Cécile, Wright, Gavin J., Kwiatkowski, Dominic P., Fairhurst, Rick M., Long, Carole A., Draper, Simon J.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493472/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493472/

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