TRAF Family Member-Associated NF-κB Activator (TANK) Induced by RANKL Negatively Regulates Osteoclasts Survival and Function
Osteoclasts are the principle bone-resorbing cells. Precise control of balanced osteoclast activity is indispensable for bone homeostasis. Osteoclast activation mediated by RANK-TRAF6 axis has been clearly identified. However, a negative regulation-machinery in osteoclast remains unclear. TRAF famil...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Ivyspring International Publisher
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492797/ |