Discovery and Evaluation of Polymorphisms in the AKT2 and AKT3 Promoter Regions for Risk of Korean Lung Cancer
AKT is a signal transduction protein that plays a central role in the tumorigenesis. There are 3 mammalian isoforms of this serine/threonine protein kinase-AKT1, AKT2, and AKT3-showing a broad tissue distribution. We first discovered 2 novel polymorphisms (AKT2 -9826 C/G and AKT3 -811 A/G), and we c...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Korea Genome Organization
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3492652/ |