The birth of the Epitranscriptome: deciphering the function of RNA modifications

Recent studies have found methyl-6-adenosine in thousands of mammalian genes, and this modification is most pronounced near the beginning of the 3' UTR. We present a perspective on current work and new single-molecule sequencing methods for detecting RNA base modifications.

Bibliographic Details
Main Authors: Saletore, Yogesh, Meyer, Kate, Korlach, Jonas, Vilfan, Igor D, Jaffrey, Samie, Mason, Christopher E
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491402/