Silencing Prion Protein in MDA-MB-435 Breast Cancer Cells Leads to Pleiotropic Cellular Responses to Cytotoxic Stimuli

Prion protein (PrP) is well studied for its pathogenic role in prion disease, but its potential contribution to other pathological processes is less understood. PrP is expressed in a variety of cancers and at least in pancreatic and breast cancers, its expression appears to be associated with poor p...

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Bibliographic Details
Main Authors: Yu, Guohua, Jiang, Liming, Xu, Yuanyuan, Guo, Hongwei, Liu, Huiyan, Zhang, Yi, Yang, Huaiyi, Yuan, Chonggang, Ma, Jiyan
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487893/