Conditional over-expression of PITX1 causes skeletal muscle dystrophy in mice
Paired-like homeodomain transcription factor 1 (PITX1) was specifically up-regulated in patients with facioscapulohumeral muscular dystrophy (FSHD) by comparing the genome-wide mRNA expression profiles of 12 neuromuscular disorders. In addition, it is the only known direct transcriptional target of...
Main Authors: | , , , , , , , , , |
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Format: | Online |
Language: | English |
Published: |
The Company of Biologists
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3486706/ |