Intravenous Delivery of Targeted Liposomes to Amyloid-β Pathology in APP/PSEN1 Transgenic Mice

Extracellular amyloid-β (Aβ) plaques and intracellular neurofibrillary tangles constitute the major neuropathological hallmarks of Alzheimer’s disease (AD). It is now apparent that parenchymal Aβ plaque deposition precedes behavioral signs of disease by several years. The development of agents that...

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Bibliographic Details
Main Authors: Tanifum, Eric A., Dasgupta, Indrani, Srivastava, Mayank, Bhavane, Rohan C., Sun, Li, Berridge, John, Pourgarzham, Hoda, Kamath, Rashmi, Espinosa, Gabriela, Cook, Stephen C., Eriksen, Jason L., Annapragada, Ananth
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3485335/