Airway Smooth Muscle Dynamics and Hyperresponsiveness: In and outside the Clinic

The primary functional abnormality in asthma is airway hyperresponsiveness (AHR)—excessive airway narrowing to bronchoconstrictor stimuli. Our understanding of the underlying mechanism(s) producing AHR is incomplete. While structure-function relationships have been evoked to explain AHR (e.g., incre...

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Bibliographic Details
Main Authors: Noble, Peter B., Ansell, Thomas K., James, Alan L., McFawn, Peter K., Mitchell, Howard W.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483736/