FZD6 is a novel gene for human neural tube defects

Neural tube defects (NTDs) are severe malformations of the central nervous system, affecting 1 of 1,000 live births. Mouse models were instrumental in defining the signaling pathways defective in NTDs, including the planar cell polarity (PCP), also called noncanonical Frizzled/Disheveled pathway. Ba...

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Bibliographic Details
Main Authors: De Marco, Patrizia, Merello, Elisa, Rossi, Andrea, Piatelli, Gianluca, Cama, Armando, Kibar, Zoha, Capra, Valeria
Format: Online
Language:English
Published: Wiley Subscription Services, Inc., A Wiley Company 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482927/