FZD6 is a novel gene for human neural tube defects
Neural tube defects (NTDs) are severe malformations of the central nervous system, affecting 1 of 1,000 live births. Mouse models were instrumental in defining the signaling pathways defective in NTDs, including the planar cell polarity (PCP), also called noncanonical Frizzled/Disheveled pathway. Ba...
Main Authors: | , , , , , , |
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Format: | Online |
Language: | English |
Published: |
Wiley Subscription Services, Inc., A Wiley Company
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482927/ |