The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes

The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes

Diabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosiner...

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Main Authors: Chia, Joanne S. J., McRae, Jennifer L., Cowan, Peter J., Dwyer, Karen M.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480695/
id pubmed-3480695
recordtype oai_dc
spelling pubmed-34806952012-11-01 The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes Chia, Joanne S. J. McRae, Jennifer L. Cowan, Peter J. Dwyer, Karen M. Review Article Diabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosinergic axis in the pathogenesis of both T1D and T2D, with particular emphasis on the role of CD39 and CD73. Hindawi Publishing Corporation 2012 2012-10-14 /pmc/articles/PMC3480695/ /pubmed/23118504 http://dx.doi.org/10.1155/2012/320495 Text en Copyright © 2012 Joanne S. J. Chia et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Chia, Joanne S. J.
McRae, Jennifer L.
Cowan, Peter J.
Dwyer, Karen M.
spellingShingle Chia, Joanne S. J.
McRae, Jennifer L.
Cowan, Peter J.
Dwyer, Karen M.
The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes
author_facet Chia, Joanne S. J.
McRae, Jennifer L.
Cowan, Peter J.
Dwyer, Karen M.
author_sort Chia, Joanne S. J.
title The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes
title_short The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes
title_full The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes
title_fullStr The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes
title_full_unstemmed The CD39-Adenosinergic Axis in the Pathogenesis of Immune and Nonimmune Diabetes
title_sort cd39-adenosinergic axis in the pathogenesis of immune and nonimmune diabetes
description Diabetes mellitus encompasses two distinct disease processes: autoimmune Type 1 (T1D) and nonimmune Type 2 (T2D) diabetes. Despite the disparate aetiologies, the disease phenotype of hyperglycemia and the associated complications are similar. In this paper, we discuss the role of the CD39-adenosinergic axis in the pathogenesis of both T1D and T2D, with particular emphasis on the role of CD39 and CD73.
publisher Hindawi Publishing Corporation
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480695/
_version_ 1611918719528730624

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