Multicomponent DNA vaccine-encoding Toxoplasma gondii GRA1 and SAG1 primes: anti-Toxoplasma immune response in mice

A multicomponent DNA vaccine, encoding Toxoplasma gondii GRA1 and SAG1, was constructed and tested for its ability to confer protection. BALB/c mice were challenged with tachyzoites of the virulent T. gondii RH strain at 4 weeks following the last immunization, and immune responses and survival time...

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Bibliographic Details
Main Authors: Wu, Xiao-Nan, Lin, Jie, Lin, Xu, Chen, Jie, Chen, Zhong-Long, Lin, Jian-Yin
Format: Online
Language:English
Published: Springer-Verlag 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480591/