Gene Transfer of Heme Oxygenase-1 Using an Adeno-Associated Virus Serotype 6 Vector Prolongs Cardiac Allograft Survival

Gene Transfer of Heme Oxygenase-1 Using an Adeno-Associated Virus Serotype 6 Vector Prolongs Cardiac Allograft Survival

Introduction. Allograft survival can be prolonged by overexpression of cytoprotective genes such as heme oxygenase-1 (HO-1). Modifications in vector design and delivery have provided new opportunities to safely and effectively administer HO-1 into the heart prior to transplantation to improve long-...

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Bibliographic Details
Main Authors: Evans, Jacqueline M., Navarro, Sonia, Doki, Tomoko, Stewart, John M., Mitsuhashi, Noboru, Kearns-Jonker, Mary
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480008/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480008/

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