Revealing mechanisms underlying variation in malaria virulence: effective propagation and host control of uninfected red blood cell supply

Malaria parasite clones with the highest transmission rates to mosquitoes also tend to induce the most severe fitness consequences (or virulence) in mammals. This is in accord with expectations from the virulence–transmission trade-off hypothesis. However, the mechanisms underlying how different clo...

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Bibliographic Details
Main Authors: Metcalf, C. J. E., Long, G. H., Mideo, N., Forester, J. D., Bjørnstad, O. N., Graham, A. L.
Format: Online
Language:English
Published: The Royal Society 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479917/