12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

We have interrogated a 12-chemokine gene expression signature (GES) on genomic arrays of 14,492 distinct solid tumors and show broad distribution across different histologies. We hypothesized that this 12-chemokine GES might accurately predict a unique intratumoral immune reaction in stage IV (non-l...

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Bibliographic Details
Main Authors: Messina, Jane L., Fenstermacher, David A., Eschrich, Steven, Qu, Xiaotao, Berglund, Anders E., Lloyd, Mark C., Schell, Michael J., Sondak, Vernon K., Weber, Jeffrey S., Mulé, James J.
Format: Online
Language:English
Published: Nature Publishing Group 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479449/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479449/

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