Cockayne Syndrome group B protein interacts with TRF2 and regulates telomere length and stability

The majority of Cockayne syndrome (CS) patients carry a mutation in Cockayne Syndrome group B (CSB), a large nuclear protein implicated in DNA repair, transcription and chromatin remodeling. However, whether CSB may play a role in telomere metabolism has not yet been characterized. Here, we report t...

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Bibliographic Details
Main Authors: Batenburg, Nicole L., Mitchell, Taylor R. H., Leach, Derrik M., Rainbow, Andrew J., Zhu, Xu-Dong
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3479199/