Silencing of miR-370 in Human Cholangiocarcinoma by Allelic Loss and Interleukin-6 Induced Maternal to Paternal Epigenotype Switch

Silencing of miR-370 in Human Cholangiocarcinoma by Allelic Loss and Interleukin-6 Induced Maternal to Paternal Epigenotype Switch

Cholangiocarcinoma (CCA) is a highly lethal malignant tumor arising from the biliary tract epithelium. Interleukin-6 (IL-6) is a major mediator of inflammation and contributor to carcinogenesis within the biliary tree. Previous studies suggested that enforced IL-6 contributes to cholangiocarcinogene...

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Bibliographic Details
Main Authors: An, Fangmei, Yamanaka, Sumitaka, Allen, Sarah, Roberts, Lewis R., Gores, Gregory J., Pawlik, Timothy M., Xie, Qing, Ishida, Masaharu, Mezey, Esteban, Ferguson-Smith, Anne C., Mori, Yuriko, Selaru, Florin M.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478287/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478287/

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