A Novel Mammal-Specific Three Partite Enhancer Element Regulates Node and Notochord-Specific Noto Expression

The vertebrate organizer and notochord have conserved, essential functions for embryonic development and patterning. The restricted expression of developmental regulators in these tissues is directed by specific cis-regulatory modules (CRMs) whose sequence conservation varies considerably. Some CRMs...

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Bibliographic Details
Main Authors: Alten, Leonie, Schuster-Gossler, Karin, Eichenlaub, Michael P., Wittbrodt, Beate, Wittbrodt, Joachim, Gossler, Achim
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478275/