Anti-Cancer Drugs Elicit Re-Expression of UDP-Glucuronosyltransferases in Melanoma Cells
The UDP-glucuronosyltransferase (UGT) family of enzymes plays a vital role in the detoxification of carcinogens as well as clearance of anti-cancer drugs. In humans, 19 UGT family members have been identified and are expressed in a tissue specific manner throughout the body. However, the UGTs have n...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Public Library of Science
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478267/ |