Dopaminergic Modulation of Effort-Related Choice Behavior as Assessed by a Progressive Ratio Chow Feeding Choice Task: Pharmacological Studies and the Role of Individual Differences

Mesolimbic dopamine (DA) is involved in behavioral activation and effort-related processes. Rats with impaired DA transmission reallocate their instrumental behavior away from food-reinforced tasks with high response requirements, and instead select less effortful food-seeking behaviors. In the pres...

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Bibliographic Details
Main Authors: Randall, Patrick A., Pardo, Marta, Nunes, Eric J., López Cruz, Laura, Vemuri, V. Kiran, Makriyannis, Alex, Baqi, Younis, Müller, Christa E., Correa, Mercè, Salamone, John D.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3478264/