Increased activity of serotonin uptake in platelets in medication overuse headache following regular intake of analgesics and triptans

We investigated the effect of chronic administration of different pain medications on the activity of the serotonin transporter (SERT) in patients with medication overuse headache (MOH). We measured the kinetic of platelet 5-HT uptake (maximal velocity, Vmax and the Michaelis–Menten constant, Km) in...

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Bibliographic Details
Main Authors: Ayzenberg, Ilya, Oberman, Mark, Leineweber, Kirsten, Franke, Leonora, Yoon, Min-Suk, Diener, Hans-Christoph, Katsarava, Zaza
Format: Online
Language:English
Published: Springer Milan 2008
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3476187/