First Discovery of Two Polyketide Synthase Genes for Mitorubrinic Acid and Mitorubrinol Yellow Pigment Biosynthesis and Implications in Virulence of Penicillium marneffei

Penicillium marneffei is the most important thermal dimorphic fungus causing respiratory, skin and systemic mycosis in China and Southeast Asia. Its genome possesses a large number of polyketide synthase (PKS) genes, which should be responsible for synthesis of secondary metabolites such as pigment...

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Bibliographic Details
Main Authors: Woo, Patrick C. Y., Lam, Ching-Wan, Tam, Emily W. T., Leung, Chris K. F., Wong, Samson S. Y., Lau, Susanna K. P., Yuen, Kwok-Yung
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475676/