Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea
Four new meroterpenes, guignardones F–I (1–4), together with two known compounds guignardones A (5) and B (6) were isolated from the endophytic fungus A1 of the mangrove plant Scyphiphora hydrophyllacea. Their structures and relative configurations were elucidated by spectroscopic data and single-cr...
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pubmed-34752682012-11-01 Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea Mei, Wen-Li Zheng, Bo Zhao, You-Xing Zhong, Hui-Ming Chen, Xun-Li Wu Zeng, Yan-Bo Dong, Wen-Hua Huang, Jiu-Li Proksch, Peter Dai, Hao-Fu Article Four new meroterpenes, guignardones F–I (1–4), together with two known compounds guignardones A (5) and B (6) were isolated from the endophytic fungus A1 of the mangrove plant Scyphiphora hydrophyllacea. Their structures and relative configurations were elucidated by spectroscopic data and single-crystal X-ray crystallography. A possible biogenetic pathway of compounds 1–6 was also proposed. All compounds were evaluated for inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus. MDPI 2012-09-17 /pmc/articles/PMC3475268/ /pubmed/23118716 http://dx.doi.org/10.3390/md10091993 Text en © 2012 by the authors; licensee MDPI, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0/ This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0/). |
repository_type |
Open Access Journal |
institution_category |
Foreign Institution |
institution |
US National Center for Biotechnology Information |
building |
NCBI PubMed |
collection |
Online Access |
language |
English |
format |
Online |
author |
Mei, Wen-Li Zheng, Bo Zhao, You-Xing Zhong, Hui-Ming Chen, Xun-Li Wu Zeng, Yan-Bo Dong, Wen-Hua Huang, Jiu-Li Proksch, Peter Dai, Hao-Fu |
spellingShingle |
Mei, Wen-Li Zheng, Bo Zhao, You-Xing Zhong, Hui-Ming Chen, Xun-Li Wu Zeng, Yan-Bo Dong, Wen-Hua Huang, Jiu-Li Proksch, Peter Dai, Hao-Fu Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea |
author_facet |
Mei, Wen-Li Zheng, Bo Zhao, You-Xing Zhong, Hui-Ming Chen, Xun-Li Wu Zeng, Yan-Bo Dong, Wen-Hua Huang, Jiu-Li Proksch, Peter Dai, Hao-Fu |
author_sort |
Mei, Wen-Li |
title |
Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea |
title_short |
Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea |
title_full |
Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea |
title_fullStr |
Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea |
title_full_unstemmed |
Meroterpenes from Endophytic Fungus A1 of Mangrove Plant Scyphiphora hydrophyllacea |
title_sort |
meroterpenes from endophytic fungus a1 of mangrove plant scyphiphora hydrophyllacea |
description |
Four new meroterpenes, guignardones F–I (1–4), together with two known compounds guignardones A (5) and B (6) were isolated from the endophytic fungus A1 of the mangrove plant Scyphiphora hydrophyllacea. Their structures and relative configurations were elucidated by spectroscopic data and single-crystal X-ray crystallography. A possible biogenetic pathway of compounds 1–6 was also proposed. All compounds were evaluated for inhibitory activity against methicillin-resistant Staphylococcus aureus (MRSA) and Staphylococcus aureus. |
publisher |
MDPI |
publishDate |
2012 |
url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3475268/ |
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1611917278514774016 |