pH-sensitive Self-associations of the N-terminal Domain of NBCe1-A Suggest a Compact Conformation under Acidic Intracellular Conditions
NBCe1-A is an integral membrane protein that cotransports Na+ and HCO3- ions across the basolateral membrane of the proximal tubule. It is essential for maintaining a homeostatic balance of cellular and blood pH. In X-ray diffraction studies, we reported that the cytoplasmic, N-terminal domain of NB...
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| Format: | Online |
| Language: | English |
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Bentham Science Publishers
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3474958/ |