Hyponatremia in Cirrhosis and End-Stage Liver Disease: Treatment with the Vasopressin V2-Receptor Antagonist Tolvaptan

Hyponatremia is common in patients with cirrhosis and portal hypertension, and is characterized by excessive renal retention of water relative to sodium due to reduced solute-free water clearance. The primary cause is increased release of arginine vasopressin. Hyponatremia is associated with increas...

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Bibliographic Details
Main Authors: Gaglio, Paul, Marfo, Kwaku, Chiodo, Joseph
Format: Online
Language:English
Published: Springer US 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3472061/