Humanized TLR4/MD-2 Mice Reveal LPS Recognition Differentially Impacts Susceptibility to Yersinia pestis and Salmonella enterica

Humanized TLR4/MD-2 Mice Reveal LPS Recognition Differentially Impacts Susceptibility to Yersinia pestis and Salmonella enterica

Although lipopolysaccharide (LPS) stimulation through the Toll-like receptor (TLR)-4/MD-2 receptor complex activates host defense against Gram-negative bacterial pathogens, how species-specific differences in LPS recognition impact host defense remains undefined. Herein, we establish how temperature...

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Bibliographic Details
Main Authors: Hajjar, Adeline M., Ernst, Robert K., Fortuno, Edgardo S., Brasfield, Alicia S., Yam, Cathy S., Newlon, Lindsay A., Kollmann, Tobias R., Miller, Samuel I., Wilson, Christopher B.
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469661/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469661/

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