Induction of HCA587-Specific Antitumor Immunity with HCA587 Protein Formulated with CpG and ISCOM in Mice

HCA587 (also known as MAGE-C2) is a “cancer-testis” antigen highly expressed in a number of malignancies with unique immunological properties, making it a promising target for tumor immunotherapy. In this report, we demonstrated that HCA587 protein, when formulated with adjuvants CpG–containing olig...

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Bibliographic Details
Main Authors: Chen, Juanjuan, Zhang, Lijie, Wen, Weigang, Hao, Jiaqing, Zeng, Pumei, Qian, Xiaoping, Zhang, Yu, Yin, Yanhui
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3469506/