Activation of Akt/protein kinase B mediates the protective effects of mechanical stretching against myocardial ischemia-reperfusion injury

Akt/protein kinase B is a well-known cell survival factor and activated by many stimuli including mechanical stretching. Therefore, we evaluated the cardioprotective effect of a brief mechanical stretching of rat hearts and determined whether activation of Akt through phosphatidylinositol 3-kinase (...

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Bibliographic Details
Main Authors: Kim, Chan-Hyung, Hao, Jia, Ahn, Hee-Yul, Kim, Si Wook
Format: Online
Language:English
Published: The Korean Society of Veterinary Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3467398/