Sirtuins and renal diseases: relationship with aging and diabetic nephropathy

Sirtuins are members of the Sir2 (silent information regulator 2) family, a group of class III deacetylases. Mammals have seven different sirtuins, SIRT1–SIRT7. Among them, SIRT1, SIRT3 and SIRT6 are induced by calorie restriction conditions and are considered anti-aging molecules. SIRT1 has been th...

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Bibliographic Details
Main Authors: Kitada, Munehiro, Kume, Shinji, Takeda-Watanabe, Ai, Kanasaki, Keizo, Koya, Daisuke
Format: Online
Language:English
Published: Portland Press Ltd. 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466784/