Urea–Water Solvation Forces on Prion Structures
Solvation forces are crucial determinants in the equilibrium between the folded and unfolded state of proteins. Particularly interesting are the solvent forces of denaturing solvent mixtures on folded and misfolded states of proteins involved in neurodegeneration. The C-terminal globular domain of t...
Main Authors: | , |
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Format: | Online |
Language: | English |
Published: |
American Chemical Society
2012
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466777/ |