The Mitochondrial Na+/Ca2+ Exchanger Upregulates Glucose Dependent Ca2+ Signalling Linked to Insulin Secretion

The Mitochondrial Na+/Ca2+ Exchanger Upregulates Glucose Dependent Ca2+ Signalling Linked to Insulin Secretion

Mitochondria mediate dual metabolic and Ca2+ shuttling activities. While the former is required for Ca2+ signalling linked to insulin secretion, the role of the latter in β cell function has not been well understood, primarily because the molecular identity of the mitochondrial Ca2+ transporters wer...

Full description

Bibliographic Details
Main Authors: Nita, Iulia I., Hershfinkel, Michal, Fishman, Daniel, Ozeri, Eyal, Rutter, Guy A., Sensi, Stefano L., Khananshvili, Daniel, Lewis, Eli C., Sekler, Israel
Format: Online
Language:English
Published: Public Library of Science 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466326/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3466326/

Similar Items