Renal Podocyte Injury in a Rat Model of Type 2 Diabetes Is Prevented by Metformin
Hyperglycemia promotes oxidative stress and hence generation of reactive oxygen species (ROS), which is known to play a crucial role in the pathogenesis of diabetic nephropathy. Metformin, an oral hypoglycemic drug, possesses antioxidant effects. The aim of this paper is to investigate the protectiv...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Hindawi Publishing Corporation
2012
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3465985/ |