Expression of protein-tyrosine phosphatases in Acute Myeloid Leukemia cells: FLT3 ITD sustains high levels of DUSP6 expression

Protein-tyrosine phosphatases (PTPs) are important regulators of cellular signaling and changes in PTP activity can contribute to cell transformation. Little is known about the role of PTPs in Acute Myeloid Leukemia (AML). The aim of this study was therefore to establish a PTP expression profile in...

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Bibliographic Details
Main Authors: Arora, Deepika, Köthe, Susanne, van den Eijnden, Monique, van Huijsduijnen, Rob Hooft, Heidel, Florian, Fischer, Thomas, Scholl, Sebastian, Tölle, Benjamin, Böhmer, Sylvia-Annette, Lennartsson, Johan, Isken, Fabienne, Müller-Tidow, Carsten, Böhmer, Frank-D
Format: Online
Language:English
Published: BioMed Central 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3464674/