A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves

Multidetector-row CT is promising for prosthetic heart valve (PHV) assessment but retrospectively ECG-gated scanning has a considerable radiation dose. Recently introduced iterative reconstruction (IR) algorithms may enable radiation dose reduction with retained image quality. Furthermore, PHV image...

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Main Authors: Habets, Jesse, Symersky, Petr, de Mol, Bas A. J. M., Mali, Willem P. Th. M., Leiner, Tim, Budde, Ricardo P. J.
Format: Online
Language:English
Published: Springer Netherlands 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463798/
id pubmed-3463798
recordtype oai_dc
spelling pubmed-34637982012-10-04 A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves Habets, Jesse Symersky, Petr de Mol, Bas A. J. M. Mali, Willem P. Th. M. Leiner, Tim Budde, Ricardo P. J. Original Paper Multidetector-row CT is promising for prosthetic heart valve (PHV) assessment but retrospectively ECG-gated scanning has a considerable radiation dose. Recently introduced iterative reconstruction (IR) algorithms may enable radiation dose reduction with retained image quality. Furthermore, PHV image quality on the CT scan mainly depends on extent of PHV artifacts. IR may decrease streak artifacts. We compared image noise and artifact volumes in scans of mechanical PHVs reconstructed with conventional filtered back projection (FBP) to lower dose scans reconstructed with IR. Four different PHVs (St. Jude, Carbomedics, ON-X and Medtronic Hall) were scanned in a pulsatile in vitro model. Ten retrospectively ECG-gated CT scans were performed of each PHV at 120 kV, 600 mAs (high-dose CTDIvol 35.3 mGy) and 120 kV, 300 mAs (low-dose CTDIvol 17.7 mGy) on a 64 detector-row scanner. Diastolic and systolic images were reconstructed with FBP (high and low-dose) and the IR algorithm (low-dose only). Hypo- and hyperdense artifact volumes were determined using two threshold filters. Image noise was measured. Mean hypo- and hyperdense artifact volumes (mm3) were 1,235/5,346 (high-dose FBP); 2,405/6,877 (low-dose FBP) and 1,218/5,333 (low-dose IR). Low-dose IR reconstructions had similar image noise compared to high-dose FBP (16.5 ± 1.7 vs. 16.3 ± 1.6, mean ± SD, respectively, P = 1.0). IR allows ECG-gated PHV imaging with similar image noise and PHV artifacts at 50% less dose compared to conventional FBP in an pulsatile in vitro model. Springer Netherlands 2011-10-15 2012-08 /pmc/articles/PMC3463798/ /pubmed/22002686 http://dx.doi.org/10.1007/s10554-011-9954-7 Text en © The Author(s) 2011
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Habets, Jesse
Symersky, Petr
de Mol, Bas A. J. M.
Mali, Willem P. Th. M.
Leiner, Tim
Budde, Ricardo P. J.
spellingShingle Habets, Jesse
Symersky, Petr
de Mol, Bas A. J. M.
Mali, Willem P. Th. M.
Leiner, Tim
Budde, Ricardo P. J.
A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves
author_facet Habets, Jesse
Symersky, Petr
de Mol, Bas A. J. M.
Mali, Willem P. Th. M.
Leiner, Tim
Budde, Ricardo P. J.
author_sort Habets, Jesse
title A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves
title_short A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves
title_full A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves
title_fullStr A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves
title_full_unstemmed A novel iterative reconstruction algorithm allows reduced dose multidetector-row CT imaging of mechanical prosthetic heart valves
title_sort novel iterative reconstruction algorithm allows reduced dose multidetector-row ct imaging of mechanical prosthetic heart valves
description Multidetector-row CT is promising for prosthetic heart valve (PHV) assessment but retrospectively ECG-gated scanning has a considerable radiation dose. Recently introduced iterative reconstruction (IR) algorithms may enable radiation dose reduction with retained image quality. Furthermore, PHV image quality on the CT scan mainly depends on extent of PHV artifacts. IR may decrease streak artifacts. We compared image noise and artifact volumes in scans of mechanical PHVs reconstructed with conventional filtered back projection (FBP) to lower dose scans reconstructed with IR. Four different PHVs (St. Jude, Carbomedics, ON-X and Medtronic Hall) were scanned in a pulsatile in vitro model. Ten retrospectively ECG-gated CT scans were performed of each PHV at 120 kV, 600 mAs (high-dose CTDIvol 35.3 mGy) and 120 kV, 300 mAs (low-dose CTDIvol 17.7 mGy) on a 64 detector-row scanner. Diastolic and systolic images were reconstructed with FBP (high and low-dose) and the IR algorithm (low-dose only). Hypo- and hyperdense artifact volumes were determined using two threshold filters. Image noise was measured. Mean hypo- and hyperdense artifact volumes (mm3) were 1,235/5,346 (high-dose FBP); 2,405/6,877 (low-dose FBP) and 1,218/5,333 (low-dose IR). Low-dose IR reconstructions had similar image noise compared to high-dose FBP (16.5 ± 1.7 vs. 16.3 ± 1.6, mean ± SD, respectively, P = 1.0). IR allows ECG-gated PHV imaging with similar image noise and PHV artifacts at 50% less dose compared to conventional FBP in an pulsatile in vitro model.
publisher Springer Netherlands
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463798/
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