PML promotes MHC class II gene expression by stabilizing the class II transactivator

PML promotes MHC class II gene expression by stabilizing the class II transactivator

Promyelocytic leukemia (PML) protein binds to and stabilizes CIITA at PML nuclear bodies, which promotes expression of the MHC class II gene locus in response to interferon-γ exposure.

Bibliographic Details
Main Authors: Ulbricht, Tobias, Alzrigat, Mohammad, Horch, Almut, Reuter, Nina, von Mikecz, Anna, Steimle, Viktor, Schmitt, Eberhard, Krämer, Oliver H., Stamminger, Thomas, Hemmerich, Peter
Format: Online
Language:English
Published: The Rockefeller University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461510/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3461510/

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