TLR9-mediated ARF6 activation is involved in advancing CpG ODN cellular uptake

Nucleic acid cellular uptake into endosomes is critical in eliciting nucleotide-sensing toll-like receptors (TLRs) innate immune responses. ADP-ribosylation factor 6 (ARF6) is a member of the Ras superfamily, which is critical to a wide variety of cellular events including endocytosis. Our previous...

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Bibliographic Details
Main Authors: Wu, Jing-Yiing, Kuo, Cheng-Chin
Format: Online
Language:English
Published: Landes Bioscience 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3460832/