Cholesteryl ester accumulation and accelerated cholesterol absorption in intestine-specific hormone sensitive lipase-null mice

Hormone sensitive lipase (HSL) regulates the hydrolysis of acylglycerols and cholesteryl esters (CE) in various cells and organs, including enterocytes of the small intestine. The physiological role of this enzyme in enterocytes, however, stayed elusive. In the present study we generated mice lackin...

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Bibliographic Details
Main Authors: Obrowsky, Sascha, Chandak, Prakash G., Patankar, Jay V., Pfeifer, Thomas, Povoden, Silvia, Schreiber, Renate, Haemmerle, Guenter, Levak-Frank, Sanja, Kratky, Dagmar
Format: Online
Language:English
Published: Elsevier Pub. Co 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459056/