Chiral multifunctional thiourea-phosphine catalyzed asymmetric [3 + 2] annulation of Morita–Baylis–Hillman carbonates with maleimides

We have developed a multifunctional thiourea-phosphine catalyzed asymmetric [3 + 2] annulation of Morita–Baylis–Hillman (MBH) carbonates with maleimides, which can efficiently construct functionalized cyclopentenes bearing three contiguous stereocenters in moderate to excellent yields and excellent...

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Bibliographic Details
Main Authors: Deng, Hong-Ping, Wang, De, Wei, Yin, Shi, Min
Format: Online
Language:English
Published: Beilstein-Institut 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3458726/